A copy of Microsoft Windows is required though. This software is simplistic and won't take up much on your time because it doesn't even require a Mac restart anytime you wish to run a Windows application. You are advised to go with the Parallel Desktop. So many software out there can help you open EXE files on Mac. You need an emulator (WINE is by far the most popular), or you install a virtual machine software on your macOS to enable you to load Windows VM or make an extra partition on your disk where you can simultaneously have both macOS and Windows in your Mac.Īgain, you have several options to choose from when attempting this. Running EXE files on Mac is very possible but only through backdoor means, so to speak.